Sr. Eusebia was born in Cantalpino (Salamanca, Spain) on December 15, 1899.
Her childhood was poor but happy, illuminated by the great faith of that very poor home, in which father, mother and sisters alternated work and prayer in an atmosphere of mutual love and charity towards everyone. In her early life she had go into service with families in her area. From her father she inherited a lively interest in the basic ideas of the Catechism.
This made it possible for her to receive the "Bread of Heaven" at the age of nine.
On that occasion Eusebia experienced something wonderful in her heart. The spark of an intense love for Jesus in the Eucharist was lighted in her heart and she found great joy in meeting Him in Communion. This love helped her to overcome every difficulty and to go beyond the tender love she had for her family in order to consecrate her life totally to God as a Salesian Sister (1924).
Destined for the house of Valverde del Camino (diocese of Huelva), she took charge of the kitchen and various other community responsibilities, giving her service in amiable and joyful availability.
In the Sunday Oratory she followed the younger children with apostolic efficacy. However, she often found herself surrounded by the older ones and even the adults, who were attracted by her spirit of prayer and by her convinced and convincing faith.
Her deep desire was to "make prayer resound in every home" so that every person might honour the Lord's Passion. Through her numerous letters, she became an untiring promoter of devotion to the Wounds of Jesus, in order to obtain mercy for all sinners. In 1931, on the eve of the revolution, Sr. Eusebia offered herself to God as a victim for the salvation of her brothers and sisters in Spain and throughout the world.
For three years she bore indescribable sufferings in a joyful crescendo of longing for Heaven, which opened its doors to her on February 10, 1935.
Her remains lie in Valverde (Huelva, Spain).
She was beatified by Pope John Paul II on April 25, 2004 in Rome. The Liturgical Memorial of Sr. Eusebia Palomino is celebrated on February 9th.